Zinc Acetate USP Grade Specifications:
C4H6O4Zn-2H2O --- 219.50
C4H6O4Zn --- 183.48
Acetic acid, zinc salt, dihydrate;
Zinc acetate dihydrate CAS 5970-45-6
Zinc acetate anhydrous CAS 557-34-6

DEFINITION
Zinc Acetate contains NLT 98.0% and NMT 102.0% of C4H6O4Zn-2H2O.

IDENTIFICATION
A. Identification Tests - General, Zinc: A 50 mg/mL solution meets the requirements.
B. Identification Tests - General, Acetate: A 50 mg/mL solution meets the requirements.
ASSAY
Procedure
Sample solution: To 400 mg of Zinc Acetate in 100 mL of water add 5 mL of ammonia-ammonium chloride buffer and 0.1 mL of eriochrome black.
Analysis: Titrate the Sample solution with 0.05 M edetate disodium until the solution is deep blue in color. Each mL of 0.05 M edetate disodium is equivalent to 10.98 mg of zinc acetate dihydrate (C4H6O4Zn-2H2O).
Acceptance criteria: 98% to 102%

Specifications of Zinc Acetate BP Ph Eur Grade:
C4H6O4Zn-2H2O --- 219.5 --- CAS 5970-45-6
Action and use: Astringent.

DEFINITION
Content: 99.0 per cent to 101.0 per cent of C4H6O4Zn,2H2O.

CHARACTERS
Appearance: White or almost white crystalline powder or flakes.
Solubility: Freely soluble in water, soluble in ethanol (96 per cent).

IDENTIFICATION
A. It gives reaction of acetates.
B. It gives the reaction of zinc.

TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water prepared from distilled water and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S is clear and colourless.
pH: 5.8 to 7.0.
Dilute 10 mL of solution S to 20 mL with carbon dioxide-free water.
Reducing substances: Boil for 5 min a mixture of 10 mL of solution S, 90 mL of water, 5 mL of dilute sulfuric acid and 1.5 mL of a 0.3 g/L solution of potassium permanganate. The pink colour of the solution remains.
Chlorides: Maximum 50 ppm.
Sulfates: Maximum 100 ppm, determined on solution S.
Aluminium: Maximum 5 ppm.
Arsenic: Maximum 2 ppm, determined on 0.5 g.
Cadmium: Maximum 2 ppm.
Copper: Maximum 50 ppm.
Iron: Maximum 50 ppm.
Lead: Maximum 10 ppm.

Specifications of Zinc Acetate Dihydrate Reagent
(CH3COO)2Zn-2H2O
Formula Weight 219.51
CAS Number 5970-45-6
REQUIREMENTS
Assay: 98.0-101.0% (CH3COO)2Zn-2H2O
pH of a 5% solution: 6.0-7.0 at 25C

Insoluble matter: 0.005%
Chloride (Cl): 5 ppm
Sulfate (SO4): 0.005%
Calcium (Ca): 0.005%
Magnesium (Mg): 0.005%
Potassium (K): 0.01%
Sodium (Na): 0.05%
Iron (Fe): 5 ppm
Lead (Pb): 0.002%.